Understandings● Taxol is a drug that is commonly used to treat several different forms of cancer.
● Taxol naturally occurs in yew trees but is now commonly synthetically produced. ● A chiral auxiliary is an optically active substance that is temporarily incorporated into an organic synthesis so that it can be carried out asymmetrically with the selective formation of a single enantiomer |
Applications and skills● Explanation of how Taxol (Paclitaxel) is obtained and used as a chemotherapeutic agent.
● Description of the use of chiral auxiliaries to form the desired enantiomer. ● Explanation of the use of a polarimeter to identify enantiomers. Guidance The structure of Taxol is provided in the IB data booklet in section 37. |
Coming soon ... |